IGF-1 LR3 – Research Grade Peptide

Lyophilised Powder | ≥99% Purity

IGF-1 LR3 (Long Arg³ IGF-1) is a synthetically manufactured research peptide supplied as a high-purity lyophilised powder. It is characterised as a modified insulin-like growth factor-1 (IGF-1) analogue and is supplied strictly for laboratory and analytical research applications.

Research Context

IGF-1 LR3 is studied in laboratory environments for its interaction with the insulin-like growth factor signalling axis. It is characterised as a long-acting IGF-1 receptor agonist analogue, engineered via:

• An arginine substitution at position 3 (Arg³)
• An additional 13–amino acid N-terminal extension (“Long”)

In experimental models, these modifications are investigated for their potential to reduce affinity for IGF-binding proteins (IGFBPs) and improve peptide stability, supporting sustained interaction with the IGF-1 receptor (IGF-1R) under controlled research conditions.

Research interest in this class of peptides primarily focuses on understanding:

• IGF-1 receptor (IGF-1R) activation and downstream signalling
• PI3K/AKT and MAPK pathway involvement in cell growth models
• Cellular proliferation, differentiation, and survival signalling in vitro
• Ligand stability and binding dynamics relative to native IGF-1

Any reference to receptor activity or biological mechanisms is provided strictly for scientific context within research settings.

Technical Specifications

Storage & Handling

• Store lyophilised peptide at2–8°C for short-term storage.
• For extended storage, keep at−20°C or below.
• Protect fromlight and moisture.
• Avoidrepeated freeze–thaw cyclesafter reconstitution.
• Use appropriatelaboratory handling procedures.
• Proper storage and handling are essential to maintain peptide integrity and stability for research applications.

Intended Use

This product is supplied strictly for laboratory and scientific research purposes only.

It is:

• Not for human consumption
• Not for animal or veterinary use
• Not a therapeutic good
• Not approved for medical, diagnostic, or clinical applications

Any reference to biological mechanisms or receptor activity is provided solely for scientific context.

Purchasers are responsible for ensuring compliance with all applicable laws and proper laboratory protocols.